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Metabolic remodeling of pyrimidine synthesis pathway and serine synthesis pathway in human glioblastoma

Glioblastoma is the most common brain tumor with dismal outcomes in adults. Metabolic remodeling is now widely acknowledged as a hallmark of cancer cells, but glioblastoma-specific metabolic pathways remain unclear. Here we show, using a large-scale targeted proteomics platform and integrated molecu...

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Detalles Bibliográficos
Autores principales: Nakamizo, Akira, Miyamatsu, Yuichiro, Hirose, Haruka, Amano, Toshiyuki, Matsuo, Satoshi, Fujiwara, Minako, Shimamura, Teppei, Yoshimoto, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522918/
https://www.ncbi.nlm.nih.gov/pubmed/36175487
http://dx.doi.org/10.1038/s41598-022-20613-w