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Protein arginine N-methyltransferase 4 (PRMT4) contributes to lymphopenia in experimental sepsis

BACKGROUND: One hallmark of sepsis is the reduced number of lymphocytes, termed lymphopenia, that occurs from decreased lymphocyte proliferation or increased cell death contributing to immune suppression. Histone modification enzymes regulate immunity by their epigenetic and non-epigenetic functions...

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Detalles Bibliográficos
Autores principales: Lai, Yandong, Li, Xiuying, Li, Tiao, Li, Xiaoyun, Nyunoya, Toru, Chen, Kong, Kitsios, Georgios, Nouraie, Mehdi, Zhang, Yingze, McVerry, Bryan J, Lee, Janet S, Mallmapalli, Rama K, Zou, Chunbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522923/
https://www.ncbi.nlm.nih.gov/pubmed/35354645
http://dx.doi.org/10.1136/thoraxjnl-2021-217526