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Protein arginine N-methyltransferase 4 (PRMT4) contributes to lymphopenia in experimental sepsis
BACKGROUND: One hallmark of sepsis is the reduced number of lymphocytes, termed lymphopenia, that occurs from decreased lymphocyte proliferation or increased cell death contributing to immune suppression. Histone modification enzymes regulate immunity by their epigenetic and non-epigenetic functions...
Autores principales: | Lai, Yandong, Li, Xiuying, Li, Tiao, Li, Xiaoyun, Nyunoya, Toru, Chen, Kong, Kitsios, Georgios, Nouraie, Mehdi, Zhang, Yingze, McVerry, Bryan J, Lee, Janet S, Mallmapalli, Rama K, Zou, Chunbin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522923/ https://www.ncbi.nlm.nih.gov/pubmed/35354645 http://dx.doi.org/10.1136/thoraxjnl-2021-217526 |
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