BMP2 promotes lung adenocarcinoma metastasis through BMP receptor 2-mediated SMAD1/5 activation

Bone morphogenetic protein 2 (BMP2) is highly overexpressed in human non-small cell lung cancer (NSCLC) and correlates with tumor stage and metastatic burden. Although several lines of evidence suggest that BMP2 promotes cell migration and invasiveness in vitro, the in vivo role of BMP2 in the metas...

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Detalles Bibliográficos
Autores principales: Wu, Cheng-Kuei, Wei, Man-Ting, Wu, Hung-Chang, Wu, Cheng-Lin, Wu, Cheng-Ju, Liaw, Hungjiun, Su, Wen-Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522928/
https://www.ncbi.nlm.nih.gov/pubmed/36175474
http://dx.doi.org/10.1038/s41598-022-20788-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522928/
https://www.ncbi.nlm.nih.gov/pubmed/36175474
http://dx.doi.org/10.1038/s41598-022-20788-2

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