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BMP2 promotes lung adenocarcinoma metastasis through BMP receptor 2-mediated SMAD1/5 activation
Bone morphogenetic protein 2 (BMP2) is highly overexpressed in human non-small cell lung cancer (NSCLC) and correlates with tumor stage and metastatic burden. Although several lines of evidence suggest that BMP2 promotes cell migration and invasiveness in vitro, the in vivo role of BMP2 in the metas...
Autores principales: | Wu, Cheng-Kuei, Wei, Man-Ting, Wu, Hung-Chang, Wu, Cheng-Lin, Wu, Cheng-Ju, Liaw, Hungjiun, Su, Wen-Pin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522928/ https://www.ncbi.nlm.nih.gov/pubmed/36175474 http://dx.doi.org/10.1038/s41598-022-20788-2 |
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