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Pharmacokinetics, efficacy and tolerance of cefoxitin in the treatment of cefoxitin-susceptible extended-spectrum beta-lactamase producing Enterobacterales infections in critically ill patients: a retrospective single-center study

BACKGROUND: Cefoxitin is active against some extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-PE), but has not been evaluated so far in the intensive care unit (ICU) settings. Data upon its pharmacokinetics (PK), tolerance and efficacy in critical conditions are scanty. We performed...

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Detalles Bibliográficos
Autores principales: Chabert, Paul, Provoost, Judith, Cohen, Sabine, Dupieux-Chabert, Céline, Bitker, Laurent, Ferry, Tristan, Goutelle, Sylvain, Richard, Jean-Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522958/
https://www.ncbi.nlm.nih.gov/pubmed/36175707
http://dx.doi.org/10.1186/s13613-022-01059-9