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Targeting bromodomain and extra-terminal proteins to inhibit neuroblastoma tumorigenesis through regulating MYCN

Bromodomain and extra-terminal domain (BET) family proteins play important roles in regulating the expression of multiple proto-oncogenes by recognizing acetylation of histones and non-histone proteins including transcription factors, which subsequently promote tumor cell proliferation, survival, me...

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Detalles Bibliográficos
Autores principales: Shi, Xiyao, Wang, Ying, Zhang, Longhui, Zhao, Wenjie, Dai, Xiangpeng, Yang, Yong-Guang, Zhang, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523081/
https://www.ncbi.nlm.nih.gov/pubmed/36187481
http://dx.doi.org/10.3389/fcell.2022.1021820