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Targeting bromodomain and extra-terminal proteins to inhibit neuroblastoma tumorigenesis through regulating MYCN
Bromodomain and extra-terminal domain (BET) family proteins play important roles in regulating the expression of multiple proto-oncogenes by recognizing acetylation of histones and non-histone proteins including transcription factors, which subsequently promote tumor cell proliferation, survival, me...
Autores principales: | Shi, Xiyao, Wang, Ying, Zhang, Longhui, Zhao, Wenjie, Dai, Xiangpeng, Yang, Yong-Guang, Zhang, Xiaoling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523081/ https://www.ncbi.nlm.nih.gov/pubmed/36187481 http://dx.doi.org/10.3389/fcell.2022.1021820 |
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