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Efficient generation of mNeonGreen Plasmodium falciparum reporter lines enables quantitative fitness analysis

CRISPR editing has enabled the rapid creation of fluorescent Plasmodium transgenic lines, facilitating a deeper understanding of parasite biology. The impact of genetic perturbations such as gene disruption or the introduction of drug resistance alleles on parasite fitness is typically quantified in...

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Detalles Bibliográficos
Autores principales: Hoshizaki, Johanna, Jagoe, Hannah, Lee, Marcus C. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523114/
https://www.ncbi.nlm.nih.gov/pubmed/36189342
http://dx.doi.org/10.3389/fcimb.2022.981432