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Efficient generation of mNeonGreen Plasmodium falciparum reporter lines enables quantitative fitness analysis
CRISPR editing has enabled the rapid creation of fluorescent Plasmodium transgenic lines, facilitating a deeper understanding of parasite biology. The impact of genetic perturbations such as gene disruption or the introduction of drug resistance alleles on parasite fitness is typically quantified in...
Autores principales: | Hoshizaki, Johanna, Jagoe, Hannah, Lee, Marcus C. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523114/ https://www.ncbi.nlm.nih.gov/pubmed/36189342 http://dx.doi.org/10.3389/fcimb.2022.981432 |
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