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Selective inhibition of soluble tumor necrosis factor signaling reduces abdominal aortic aneurysm progression

BACKGROUND: Tumor necrosis factor (TNF) is pathologically elevated in human abdominal aortic aneurysms (AAA). Non-selective TNF inhibition-based therapeutics are approved for human use but have been linked to several side effects. Compounds that target the proinflammatory soluble form of TNF (solTNF...

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Detalles Bibliográficos
Autores principales: Griepke, Silke, Grupe, Emilie, Lindholt, Jes Sanddal, Fuglsang, Elizabeth Hvitfeldt, Steffensen, Lasse Bach, Beck, Hans Christian, Larsen, Mia Dupont, Bang-Møller, Sissel Karoline, Overgaard, Martin, Rasmussen, Lars Melholt, Lambertsen, Kate Lykke, Stubbe, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523116/
https://www.ncbi.nlm.nih.gov/pubmed/36186984
http://dx.doi.org/10.3389/fcvm.2022.942342