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Selective inhibition of soluble tumor necrosis factor signaling reduces abdominal aortic aneurysm progression
BACKGROUND: Tumor necrosis factor (TNF) is pathologically elevated in human abdominal aortic aneurysms (AAA). Non-selective TNF inhibition-based therapeutics are approved for human use but have been linked to several side effects. Compounds that target the proinflammatory soluble form of TNF (solTNF...
Autores principales: | Griepke, Silke, Grupe, Emilie, Lindholt, Jes Sanddal, Fuglsang, Elizabeth Hvitfeldt, Steffensen, Lasse Bach, Beck, Hans Christian, Larsen, Mia Dupont, Bang-Møller, Sissel Karoline, Overgaard, Martin, Rasmussen, Lars Melholt, Lambertsen, Kate Lykke, Stubbe, Jane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523116/ https://www.ncbi.nlm.nih.gov/pubmed/36186984 http://dx.doi.org/10.3389/fcvm.2022.942342 |
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