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Apamin structure and pharmacology revisited

Apamin is often cited as one of the few substances selectively acting on small-conductance Ca(2+)-activated potassium channels (K(Ca)2). However, published pharmacological and structural data remain controversial. Here, we investigated the molecular pharmacology of apamin by two-electrode voltage-cl...

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Detalles Bibliográficos
Autores principales: Kuzmenkov, Alexey I., Peigneur, Steve, Nasburg, Joshua A., Mineev, Konstantin S., Nikolaev, Maxim V., Pinheiro-Junior, Ernesto Lopes, Arseniev, Alexander S., Wulff, Heike, Tytgat, Jan, Vassilevski, Alexander A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523135/
https://www.ncbi.nlm.nih.gov/pubmed/36188602
http://dx.doi.org/10.3389/fphar.2022.977440