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Absence of the Fragile X messenger ribonucleoprotein alters response patterns to sounds in the auditory midbrain

Among the different autism spectrum disorders, Fragile X syndrome (FXS) is the most common inherited cause of intellectual disability. Sensory and especially auditory hypersensitivity is a key symptom in patients, which is well mimicked in the Fmr1 -/- mouse model. However, the physiological mechani...

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Detalles Bibliográficos
Autores principales: Sibille, Jérémie, Kremkow, Jens, Koch, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523263/
https://www.ncbi.nlm.nih.gov/pubmed/36188480
http://dx.doi.org/10.3389/fnins.2022.987939