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A methylbenzimidazole derivative regulates mammalian circadian rhythms by targeting Cryptochrome proteins

Background: Impairment of the circadian clock has been associated with numerous diseases, including sleep disorders and metabolic disease. Although small molecules that modulate clock function may form the basis of drug discovery of clock-related diseases, only a few compounds that selectively targe...

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Detalles Bibliográficos
Autores principales: Yagi, Moeri, Miller, Simon, Nagai, Yoshiko, Inuki, Shinsuke, Sato, Ayato, Hirota, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523283/
https://www.ncbi.nlm.nih.gov/pubmed/36226040
http://dx.doi.org/10.12688/f1000research.124658.2