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Dexamethasone enhances glucose uptake by SGLT1 and GLUT1 and boosts ATP generation through the PPP-TCA cycle in bovine neutrophils

BACKGROUND: Clinical dexamethasone (DEX) treatment or stress in bovines results in extensive physiological changes with prominent hyperglycemia and neutrophils dysfunction. OBJECTIVES: To elucidate the effects of DEX treatment in vivo on cellular energy status and the underlying mechanism in circula...

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Detalles Bibliográficos
Autores principales: Wang, Xinbo, Tang, Mingyu, Zhang, Yuming, Li, Yansong, Mao, Jingdong, Deng, Qinghua, Li, Shusen, Jia, Zhenwei, Du, Liyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Veterinary Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523333/
https://www.ncbi.nlm.nih.gov/pubmed/36174980
http://dx.doi.org/10.4142/jvs.22112