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Epigallocatechin-3-gallate suppresses hemin-aggravated colon carcinogenesis through Nrf2-inhibited mitochondrial reactive oxygen species accumulation

BACKGROUND: Previous studies have presented evidence to support the significant association between red meat intake and colon cancer, suggesting that heme iron plays a key role in colon carcinogenesis. Epigallocatechin-3-gallate (EGCG), the major constituent of green tea, exhibits anti-oxidative and...

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Detalles Bibliográficos
Autores principales: Seok, Ju Hyung, Kim, Dae Hyun, Kim, Hye Jih, Jo, Hang Hyo, Kim, Eun Young, Jeong, Jae-Hwang, Park, Young Seok, Lee, Sang Hun, Kim, Dae Joong, Nam, Sang Yoon, Lee, Beom Jun, Lee, Hyun Jik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Veterinary Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523342/
https://www.ncbi.nlm.nih.gov/pubmed/36174978
http://dx.doi.org/10.4142/jvs.22097