Deficiency of peroxisomal NUDT7 stimulates de novo lipogenesis in hepatocytes

Here, we found that heterozygous null of peroxisomal Nudt7 (Nudt7(+/−)) induced the typical NAFLD features, i.e. increased levels of hepatic triglyceride (TG) and fatty acid (FA), infiltration of inflammatory cells, impaired glucose tolerance and insulin sensitivity, and stimulation of lipolysis fro...

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Detalles Bibliográficos
Autores principales: Song, Jinsoo, Baek, In-Jeoung, Park, Sujeong, Oh, Jinjoo, Kim, Deokha, Song, Kyung, Kim, Mi Kyung, Lee, Hye Won, Jang, Byoung Kuk, Jin, Eun-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523354/
https://www.ncbi.nlm.nih.gov/pubmed/36185359
http://dx.doi.org/10.1016/j.isci.2022.105135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523354/
https://www.ncbi.nlm.nih.gov/pubmed/36185359
http://dx.doi.org/10.1016/j.isci.2022.105135

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