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Ca(2+)-stimulated adenylyl cyclases as therapeutic targets for psychiatric and neurodevelopmental disorders
As the main secondary messengers, cyclic AMP (cAMP) and Ca(2+) trigger intracellular signal transduction cascade and, in turn, regulate many aspects of cellular function in developing and mature neurons. The group I adenylyl cyclase (ADCY, also known as AC) isoforms, including ADCY1, 3, and 8 (also...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523369/ https://www.ncbi.nlm.nih.gov/pubmed/36188604 http://dx.doi.org/10.3389/fphar.2022.949384 |