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Ca(2+)-stimulated adenylyl cyclases as therapeutic targets for psychiatric and neurodevelopmental disorders

As the main secondary messengers, cyclic AMP (cAMP) and Ca(2+) trigger intracellular signal transduction cascade and, in turn, regulate many aspects of cellular function in developing and mature neurons. The group I adenylyl cyclase (ADCY, also known as AC) isoforms, including ADCY1, 3, and 8 (also...

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Detalles Bibliográficos
Autores principales: Chen, Jiao, Ding, Qi, An, Lulu, Wang, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523369/
https://www.ncbi.nlm.nih.gov/pubmed/36188604
http://dx.doi.org/10.3389/fphar.2022.949384