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Immunopeptidome of hepatocytes isolated from patients with HBV infection and hepatocellular carcinoma

BACKGROUND & AIMS: Antigen-specific immunotherapy is a promising strategy to treat HBV infection and hepatocellular carcinoma (HCC). To facilitate killing of malignant and/or infected hepatocytes, it is vital to know which T cell targets are presented by human leucocyte antigen (HLA)-I complexes...

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Detalles Bibliográficos
Autores principales: de Beijer, Monique T.A., Bezstarosti, Karel, Luijten, Robbie, Doff, Wouter A.S., Boor, Patrick P.C., Pieterman, Roel F.A., Bouzid, Rachid, Biesta, Paula J., Ijzermans, Jan N.M., Doukas, Michail, de Man, Robert A., Woltman, Andrea M., Demmers, Jeroen A.A., Buschow, Sonja I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523389/
https://www.ncbi.nlm.nih.gov/pubmed/36185575
http://dx.doi.org/10.1016/j.jhepr.2022.100576