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Targeting 4-1BB for tumor immunotherapy from bench to bedside

Immune dysfunction has been proposed as a factor that may contribute to disease progression. Emerging evidence suggests that immunotherapy aims to abolish cancer progression by modulating the balance of the tumor microenvironment. 4-1BB (also known as CD137 and TNFRS9), a member of tumor necrosis fa...

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Detalles Bibliográficos
Autores principales: Wang, Ya-Tao, Ji, Wei-Dong, Jiao, Hong-Mei, Lu, Ang, Chen, Kun-Feng, Liu, Qi-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523430/
https://www.ncbi.nlm.nih.gov/pubmed/36189243
http://dx.doi.org/10.3389/fimmu.2022.975926