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Mechanical properties of the premature lung: From tissue deformation under load to mechanosensitivity of alveolar cells

Many preterm infants require mechanical ventilation as life-saving therapy. However, ventilation-induced overpressure can result in lung diseases. Considering the lung as a viscoelastic material, positive pressure inside the lung results in increased hydrostatic pressure and tissue compression. To e...

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Detalles Bibliográficos
Autores principales: Naumann, Jonas, Koppe, Nicklas, Thome, Ulrich H., Laube, Mandy, Zink, Mareike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523442/
https://www.ncbi.nlm.nih.gov/pubmed/36185437
http://dx.doi.org/10.3389/fbioe.2022.964318