TMBcat: A multi-endpoint p-value criterion on different discrepancy metrics for superiorly inferring tumor mutation burden thresholds

Tumor mutation burden (TMB) is a widely recognized stratification biomarker for predicting the efficacy of immunotherapy; however, the number and universal definition of the categorizing thresholds remain debatable due to the multifaceted nature of efficacy and the imprecision of TMB measurements. W...

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Detalles Bibliográficos
Autores principales: Wang, Yixuan, Lai, Xin, Wang, Jiayin, Xu, Ying, Zhang, Xuanping, Zhu, Xiaoyan, Liu, Yuqian, Shao, Yang, Zhang, Li, Fang, Wenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523486/
https://www.ncbi.nlm.nih.gov/pubmed/36189291
http://dx.doi.org/10.3389/fimmu.2022.995180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523486/
https://www.ncbi.nlm.nih.gov/pubmed/36189291
http://dx.doi.org/10.3389/fimmu.2022.995180

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