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TMBcat: A multi-endpoint p-value criterion on different discrepancy metrics for superiorly inferring tumor mutation burden thresholds
Tumor mutation burden (TMB) is a widely recognized stratification biomarker for predicting the efficacy of immunotherapy; however, the number and universal definition of the categorizing thresholds remain debatable due to the multifaceted nature of efficacy and the imprecision of TMB measurements. W...
Autores principales: | Wang, Yixuan, Lai, Xin, Wang, Jiayin, Xu, Ying, Zhang, Xuanping, Zhu, Xiaoyan, Liu, Yuqian, Shao, Yang, Zhang, Li, Fang, Wenfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523486/ https://www.ncbi.nlm.nih.gov/pubmed/36189291 http://dx.doi.org/10.3389/fimmu.2022.995180 |
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