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One-pot synthesis and enzyme-responsiveness of amphiphilic doxorubicin prodrug nanomicelles for cancer therapeutics

In this study, we report a one-pot synthesis and enzyme-responsiveness of polyethylene glycol (PEG) and glutamic acid (Glu)-based amphiphilic doxorubicin (DOX) prodrug nanomicelles for cancer therapeutics. The nanomicelles were accomplished by esterification and amidation reactions. The nuclear magn...

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Detalles Bibliográficos
Autores principales: Han, Ling-Na, Wang, Kai-Qiang, Ren, Zi-Ning, Yang, Xue, Duan, Xiao, Krishnan, Sasirekha, Jaisankar, Abinaya, Park, Jeong-Hui, Dashnyam, Khandmaa, Zhang, Wujie, Pedraz, José Luis, Ramakrishna, Seeram, Kim, Hae-Won, Li, Chang-Feng, Song, Li-Hua, Ramalingam, Murugan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523663/
https://www.ncbi.nlm.nih.gov/pubmed/36320274
http://dx.doi.org/10.1039/d2ra04436f