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Development and in vivo validation of small interfering RNAs targeting NOX3 to prevent sensorineural hearing loss
The reactive oxygen species (ROS)-generating enzyme NOX3 has recently been implicated in the pathophysiology of several acquired forms of sensorineural hearing loss, including cisplatin-, noise- and age-related hearing loss. NOX3 is highly and specifically expressed in the inner ear and therefore re...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523672/ https://www.ncbi.nlm.nih.gov/pubmed/36188374 http://dx.doi.org/10.3389/fneur.2022.993017 |