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Nanoscale Tracking Combined with Cell-Scale Microrheology Reveals Stepwise Increases in Force Generated by Cancer Cell Protrusions
[Image: see text] In early breast cancer progression, cancer cells invade through a nanoporous basement membrane (BM) as a first key step toward metastasis. This invasion is thought to be mediated by a combination of proteases, which biochemically degrade BM matrix, and physical forces, which mechan...
Autores principales: | Sikic, Luka, Schulman, Ester, Kosklin, Anna, Saraswathibhatla, Aashrith, Chaudhuri, Ovijit, Pokki, Juho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523704/ https://www.ncbi.nlm.nih.gov/pubmed/35950832 http://dx.doi.org/10.1021/acs.nanolett.2c01327 |
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