Splicing factor SRSF1 is essential for CD8 T cell function and host antigen-specific viral immunity

Cytotoxic CD8 T cells are crucial for the host antigen-specific immune response to viral pathogens. Here we report the identification of an essential role for the serine/arginine-rich splicing factor (SRSF) 1 in CD8 T cell homeostasis and function. Specifically, SRSF1 is necessary for the maintenanc...

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Detalles Bibliográficos
Autores principales: Juarez, Ignacio, Su, Shi, Herbert, Zachary T., Teijaro, John R., Moulton, Vaishali R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523749/
https://www.ncbi.nlm.nih.gov/pubmed/36189299
http://dx.doi.org/10.3389/fimmu.2022.906355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523749/
https://www.ncbi.nlm.nih.gov/pubmed/36189299
http://dx.doi.org/10.3389/fimmu.2022.906355

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