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Concomitant medication of cetirizine in advanced melanoma could enhance anti-PD-1 efficacy by promoting M1 macrophages polarization

BACKGROUND: The clinical observation showed a potential additive effect of anti-PD-1 agents and cetirizine in patients with advanced melanoma. METHODS: Clinical outcomes of concomitant cetirizine/anti-PD-1 treatment of patients with stage IIIb–IV melanoma were retrospectively collected, and a transc...

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Detalles Bibliográficos
Autores principales: Mallardo, Domenico, Simeone, Ester, Vanella, Vito, Vitale, Maria Grazia, Palla, Marco, Scarpato, Luigi, Paone, Miriam, De Cristofaro, Teresa, Borzillo, Valentina, Cortellini, Alessio, Sparano, Francesca, Pignata, Sandro, Fiore, Francesco, Caracò, Corrado, Maiolino, Piera, Petrillo, Antonella, Cavalcanti, Ernesta, Lastoria, Secondo, Muto, Paolo, Budillon, Alfredo, Warren, Sarah, Ascierto, Paolo Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523893/
https://www.ncbi.nlm.nih.gov/pubmed/36180872
http://dx.doi.org/10.1186/s12967-022-03643-w