Role of N-Glycosylation in FcγRIIIa interaction with IgG

Immunoglobulins G (IgG) and their Fc gamma receptors (FcγRs) play important roles in our immune system. The conserved N-glycan in the Fc region of IgG1 impacts interaction of IgG with FcγRs and the resulting effector functions, which has led to the design of antibody therapeutics with greatly improv...

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Detalles Bibliográficos
Autores principales: Van Coillie, Julie, Schulz, Morten A., Bentlage, Arthur E. H., de Haan, Noortje, Ye, Zilu, Geerdes, Dionne M., van Esch, Wim J. E., Hafkenscheid, Lise, Miller, Rebecca L., Narimatsu, Yoshiki, Vakhrushev, Sergey Y., Yang, Zhang, Vidarsson, Gestur, Clausen, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524020/
https://www.ncbi.nlm.nih.gov/pubmed/36189205
http://dx.doi.org/10.3389/fimmu.2022.987151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524020/
https://www.ncbi.nlm.nih.gov/pubmed/36189205
http://dx.doi.org/10.3389/fimmu.2022.987151

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