5-Methoxyflavone-induced AMPKα activation inhibits NF-κB and P38 MAPK signaling to attenuate influenza A virus-mediated inflammation and lung injury in vitro and in vivo

Influenza-related acute lung injury (ALI) is a life-threatening condition that results mostly from uncontrolled replication of influenza virus (IV) and severe proinflammatory responses. The methoxy flavonoid compound 5-methoxyflavone (5-MF) is believed to have superior biological activity in the tre...

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Detalles Bibliográficos
Autores principales: Yang, Sushan, Wang, Linxin, Pan, Xiping, Liang, Yueyun, Zhang, Yuehan, Li, Jing, Zhou, Beixian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524045/
https://www.ncbi.nlm.nih.gov/pubmed/36180831
http://dx.doi.org/10.1186/s11658-022-00381-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524045/
https://www.ncbi.nlm.nih.gov/pubmed/36180831
http://dx.doi.org/10.1186/s11658-022-00381-1

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