miR-146a-5p-modified hUCMSC-derived exosomes facilitate spinal cord function recovery by targeting neurotoxic astrocytes

BACKGROUND: Acute spinal cord injury (SCI) is a devastating result of neurological trauma with subsequent microenvironment dyshomeostasis that induces neurotoxic phenotype acquisition by astrocytes, exacerbating neurological function impairment. Exosomes derived from human umbilical cord mesenchymal...

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Detalles Bibliográficos
Autores principales: Lai, Xunwei, Wang, Yang, wang, Xiaokang, Liu, Bin, Rong, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524140/
https://www.ncbi.nlm.nih.gov/pubmed/36175984
http://dx.doi.org/10.1186/s13287-022-03116-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524140/
https://www.ncbi.nlm.nih.gov/pubmed/36175984
http://dx.doi.org/10.1186/s13287-022-03116-3

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