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Open channel block of Kv1.5 channels by HMQ1611
Kv1.5 channels conduct the ultra-rapid delayed rectifier potassium current (I (Kur)). Pharmacological blockade of human Kv1.5 (hKv1.5) has been regarded as an effective treatment of re-entrant based atrial fibrillation, because Kv1.5 is highly expressed in human cardiac atria but scarcely in ventric...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524145/ https://www.ncbi.nlm.nih.gov/pubmed/36188606 http://dx.doi.org/10.3389/fphar.2022.965086 |