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Open channel block of Kv1.5 channels by HMQ1611

Kv1.5 channels conduct the ultra-rapid delayed rectifier potassium current (I (Kur)). Pharmacological blockade of human Kv1.5 (hKv1.5) has been regarded as an effective treatment of re-entrant based atrial fibrillation, because Kv1.5 is highly expressed in human cardiac atria but scarcely in ventric...

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Detalles Bibliográficos
Autores principales:	Dong, Chao, Li, Jiawei, Ding, Weiguang, Ueda, Rika, Xie, Xiaolu, Wu, Jie, Matsuura, Hiroshi, Horie, Minoru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524145/ https://www.ncbi.nlm.nih.gov/pubmed/36188606 http://dx.doi.org/10.3389/fphar.2022.965086

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