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Treatment-associated remodeling of the pancreatic cancer endothelium at single-cell resolution

Pancreatic ductal adenocarcinoma (PDAC) is one of the most treatment refractory and lethal malignancies. The diversity of endothelial cell (EC) lineages in the tumor microenvironment (TME) impacts the efficacy of antineoplastic therapies, which in turn remodel EC states and distributions. Here, we p...

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Detalles Bibliográficos
Autores principales: Shiau, Carina, Su, Jennifer, Guo, Jimmy A., Hong, Theodore S., Wo, Jennifer Y., Jagadeesh, Karthik A., Hwang, William L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524152/
https://www.ncbi.nlm.nih.gov/pubmed/36185212
http://dx.doi.org/10.3389/fonc.2022.929950