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Retinal organoids and microfluidic chip-based approaches to explore the retinitis pigmentosa with USH2A mutations

Retinitis pigmentosa (RP) is a leading cause of vision impairment and blindness worldwide, with limited medical treatment options. USH2A mutations are one of the most common causes of non-syndromic RP. In this study, we developed retinal organoids (ROs) and retinal pigment epithelium (RPE) cells fro...

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Detalles Bibliográficos
Autores principales: Su, Ting, Liang, Liying, Zhang, Lan, Wang, Jianing, Chen, Luyin, Su, Caiying, Cao, Jixing, Yu, Quan, Deng, Shuai, Chan, Hon Fai, Tang, Shibo, Guo, Yonglong, Chen, Jiansu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524156/
https://www.ncbi.nlm.nih.gov/pubmed/36185441
http://dx.doi.org/10.3389/fbioe.2022.939774