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Type-I Interferon Signaling Is Essential for Robust Metronomic Chemo-Immunogenic Tumor Regression in Murine Breast Cancer

Many patients with breast cancer have a poor prognosis with limited therapeutic options. Here, we investigated the potential of chemo-immunogenic therapy as an avenue of treatment. We utilized two syngeneic mouse mammary tumor models, 4T1 and E0771, to examine the chemo-immunogenic potential of cycl...

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Detalles Bibliográficos
Autores principales: Vergato, Cameron, Doshi, Kshama A., Roblyer, Darren, Waxman, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524291/
https://www.ncbi.nlm.nih.gov/pubmed/36187936
http://dx.doi.org/10.1158/2767-9764.CRC-21-0148