BRCA1-Associated RING Domain-1 (BARD1) Loss and GBP1 Expression Enhance Sensitivity to DNA Damage in Ewing Sarcoma

Ewing sarcoma is a fusion oncoprotein–driven primary bone tumor. A subset of patients (∼10%) with Ewing sarcoma are known to harbor germline variants in a growing number of genes involved in DNA damage repair. We recently reported our discovery of a germline mutation in the DNA damage repair protein...

Descripción completa

Detalles Bibliográficos
Autores principales: Maurer, Lisa M., Daley, Jessica D., Mukherjee, Elina, Venier, Rosemarie E., Julian, Claire M., Bailey, Nathanael G., Jacobs, Michelle F., Kumar-Sinha, Chandan, Raphael, Haley, Periyapatna, Nivitha, Weiss, Kurt, Janeway, Katherine A., Mody, Rajen, Lucas, Peter C., McAllister-Lucas, Linda M., Bailey, Kelly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524505/
https://www.ncbi.nlm.nih.gov/pubmed/36187937
http://dx.doi.org/10.1158/2767-9764.CRC-21-0047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524505/
https://www.ncbi.nlm.nih.gov/pubmed/36187937
http://dx.doi.org/10.1158/2767-9764.CRC-21-0047

Ejemplares similares