Quality assurance of hematopoietic stem cells by macrophages determines stem cell clonality

Tissue-specific stem cells persist for a lifetime and can differentiate to maintain homeostasis or transform to initiate cancer. Despite their importance, there are no described quality assurance mechanisms for newly formed stem cells. We observed intimate and specific interactions between macrophag...

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Detalles Bibliográficos
Autores principales: Wattrus, Samuel J., Smith, Mackenzie L., Rodrigues, Cecilia Pessoa, Hagedorn, Elliott J., Kim, Ji Wook, Budnik, Bogdan, Zon, Leonard I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524573/
https://www.ncbi.nlm.nih.gov/pubmed/36137040
http://dx.doi.org/10.1126/science.abo4837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524573/
https://www.ncbi.nlm.nih.gov/pubmed/36137040
http://dx.doi.org/10.1126/science.abo4837

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