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Quality assurance of hematopoietic stem cells by macrophages determines stem cell clonality
Tissue-specific stem cells persist for a lifetime and can differentiate to maintain homeostasis or transform to initiate cancer. Despite their importance, there are no described quality assurance mechanisms for newly formed stem cells. We observed intimate and specific interactions between macrophag...
Autores principales: | Wattrus, Samuel J., Smith, Mackenzie L., Rodrigues, Cecilia Pessoa, Hagedorn, Elliott J., Kim, Ji Wook, Budnik, Bogdan, Zon, Leonard I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524573/ https://www.ncbi.nlm.nih.gov/pubmed/36137040 http://dx.doi.org/10.1126/science.abo4837 |
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