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Expression variation of OGG1 and HPRT gene and DNA damage in arsenic exposed industrial workers

Arsenic exposure alters redox balance, induces DNA damage, and deregulates many genes. OGG1 gene involved in base repair mechanism, for excision of 8-oxoguanine (8-oxoG) from DNA formed as a result of accumulation of ROS in cell. HPRT gene encode transferase enzymes involved in purine recycling mech...

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Detalles Bibliográficos
Autores principales: Akram, Zertashia, Mahjabeen, Ishrat, Umair, Muhammad, Fahim, Muhammad, Kayani, Mahmood Akhter, Fatima, Lulu, Ahmad, Malik Waqar, Jahan, Sarwat, Afsar, Tayyaba, Almajwal, Ali, Alruwaili, Nawaf W., Khawar, Iftikhar Ali, Razak, Suhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524634/
https://www.ncbi.nlm.nih.gov/pubmed/36178927
http://dx.doi.org/10.1371/journal.pone.0273211