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Individualised computational modelling of immune mediated disease onset, flare and clearance in psoriasis
Despite increased understanding about psoriasis pathophysiology, currently there is a lack of predictive computational models. We developed a personalisable ordinary differential equations model of human epidermis and psoriasis that incorporates immune cells and cytokine stimuli to regulate the tran...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524682/ https://www.ncbi.nlm.nih.gov/pubmed/36178923 http://dx.doi.org/10.1371/journal.pcbi.1010267 |