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A change of PD-1/PD-L1 expression on peripheral T cell subsets correlates with the different stages of Alzheimer's Disease

BACKGROUND: Immune checkpoints are a set of costimulatory and inhibitory molecules that maintain self-tolerance and regulate immune homeostasis. The expression of immune checkpoints on T cells in malignancy, chronic inflammation, and neurodegenerative diseases has gained increasing attention. RESULT...

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Detalles Bibliográficos
Autores principales: Wu, Ching-Tse, Chu, Cheng-I, Wang, Feng-Yu, Yang, Hui-Yu, Tseng, Wei-Sung, Chang, Chuang-Rung, Chang, Chien-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524741/
https://www.ncbi.nlm.nih.gov/pubmed/36180897
http://dx.doi.org/10.1186/s13578-022-00897-1