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Nanoparticle-mediated Delivery of IL-2 To T Follicular Helper Cells Protects BDF1 Mice from Lupus-like Disease

We recently reported that poly lactic-co-glycolic acid (PLGA) nanoparticles (NPs) loaded with interleukin (IL)-2 and targeted to T cells inhibited the development of lupus-like disease in BDF1 mice by inducing functional T regulatory cells (Tregs). Here we show that the protection from disease and t...

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Detalles Bibliográficos
Autores principales: Ferretti, Concetta, Horwitz, David A., Bickerton, Sean, La Cava, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524795/
https://www.ncbi.nlm.nih.gov/pubmed/36465067
http://dx.doi.org/10.2478/rir-2021-0024