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Astrocytic NDRG2-PPM1A interaction exacerbates blood-brain barrier disruption after subarachnoid hemorrhage

Blood-brain barrier (BBB) injury critically exacerbates the poor prognosis of patients with subarachnoid hemorrhage (SAH). The massively increased matrix metalloproteinases 9 (MMP-9) plays a deleterious role in BBB. However, the main source and mechanism of MMP-9 production after SAH remain unclear....

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Detalles Bibliográficos
Autores principales: Feng, Dayun, Zhou, Jinpeng, Liu, Haixiao, Wu, Xun, Li, Fei, Zhao, Junlong, Zhang, Yu, Wang, Lei, Chao, Min, Wang, Qiang, Qin, Huaizhou, Ge, Shunnan, Liu, Qiang, Zhang, Jian, Qu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524825/
https://www.ncbi.nlm.nih.gov/pubmed/36179025
http://dx.doi.org/10.1126/sciadv.abq2423