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Regulation of autoimmune disease progression by Pik3ip1 through metabolic reprogramming in T cells and therapeutic implications

Metabolic alterations could profoundly affect immune functions and influence the progression and outcome of autoimmune diseases. However, the detailed mechanisms and their therapeutic potential remain to be defined. Here, we show that phosphatidylinositide 3-kinase interacting protein 1 (Pik3ip1), a...

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Detalles Bibliográficos
Autores principales: Xie, Wenqiang, Fang, Juan, Shan, Zhongyan, Guo, Junyi, Liao, Yuan, Zou, Zhaolei, Wang, Jun, Wen, Shuqiong, Yang, Lisa, Zhang, Yanshu, Lu, Huanzi, Zhao, Hang, Kuang, Dong-Ming, Huang, Peng, Chen, Qianming, Wang, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524833/
https://www.ncbi.nlm.nih.gov/pubmed/36179018
http://dx.doi.org/10.1126/sciadv.abo4250