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Modular derivation of diverse, regionally discrete human posterior CNS neurons enables discovery of transcriptomic patterns
Our inability to derive the neuronal diversity that comprises the posterior central nervous system (pCNS) using human pluripotent stem cells (hPSCs) poses an impediment to understanding human neurodevelopment and disease in the hindbrain and spinal cord. Here, we establish a modular, monolayer diffe...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524835/ https://www.ncbi.nlm.nih.gov/pubmed/36179024 http://dx.doi.org/10.1126/sciadv.abn7430 |