Modular derivation of diverse, regionally discrete human posterior CNS neurons enables discovery of transcriptomic patterns

Our inability to derive the neuronal diversity that comprises the posterior central nervous system (pCNS) using human pluripotent stem cells (hPSCs) poses an impediment to understanding human neurodevelopment and disease in the hindbrain and spinal cord. Here, we establish a modular, monolayer diffe...

Descripción completa

Detalles Bibliográficos
Autores principales: Iyer, Nisha R., Shin, Junha, Cuskey, Stephanie, Tian, Yucheng, Nicol, Noah R., Doersch, Tessa E., Seipel, Frank, McCalla, Sunnie Grace, Roy, Sushmita, Ashton, Randolph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524835/
https://www.ncbi.nlm.nih.gov/pubmed/36179024
http://dx.doi.org/10.1126/sciadv.abn7430

Ejemplares similares

Ejemplares similares