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DNA methylome combined with chromosome cluster-oriented analysis provides an early signature for cutaneous melanoma aggressiveness

Aberrant DNA methylation is a well-known feature of tumours and has been associated with metastatic melanoma. However, since melanoma cells are highly heterogeneous, it has been challenging to use affected genes to predict tumour aggressiveness, metastatic evolution, and patients’ outcomes. We hypot...

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Detalles Bibliográficos
Autores principales: Carrier, Arnaud, Desjobert, Cécile, Ponger, Loic, Lamant, Laurence, Bustos, Matias, Torres-Ferreira, Jorge, Henrique, Rui, Jeronimo, Carmen, Lanfrancone, Luisa, Delmas, Audrey, Favre, Gilles, Daunay, Antoine, Busato, Florence, Hoon, Dave SB, Tost, Jorg, Etievant, Chantal, Riond, Joëlle, Arimondo, Paola B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525058/
https://www.ncbi.nlm.nih.gov/pubmed/36125262
http://dx.doi.org/10.7554/eLife.78587