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Memory persistence and differentiation into antibody-secreting cells accompanied by positive selection in longitudinal BCR repertoires

The stability and plasticity of B cell-mediated immune memory ensures the ability to respond to the repeated challenges. We have analyzed the longitudinal dynamics of immunoglobulin heavy chain repertoires from memory B cells, plasmablasts, and plasma cells from the peripheral blood of generally hea...

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Detalles Bibliográficos
Autores principales: Mikelov, Artem, Alekseeva, Evgeniia I, Komech, Ekaterina A, Staroverov, Dmitry B, Turchaninova, Maria A, Shugay, Mikhail, Chudakov, Dmitriy M, Bazykin, Georgii A, Zvyagin, Ivan V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9525062/
https://www.ncbi.nlm.nih.gov/pubmed/36107479
http://dx.doi.org/10.7554/eLife.79254